Defining genomic mechanisms associated with treatment response, drug resistance and early blast crisis in chronic myeloid leukaemia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1117718

Funding Status
Closed

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Funded Activity Summary

Chronic myeloid leukaemia is a fatal disease if untreated. Most patients now survive with new drugs, but some still rapidly die. I aim to understand these differences by investigating the genetic makeup of patients at diagnosis. Some may have gene mutations that prevent drugs from working effectively. Mutations will be detected using technology that can search more than 30,000 genes at the same time. This work could lead to improved survival for more patients by finding new targets for therapy.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Research Fellowships

Funding Amount: $631,370.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Genetics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA sequencing | chronic myeloid leukaemia (CML) | gene mutations | mutation detection | outcome measures

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