Dissecting human B-cell function: from primary immunodeficiencies to chronic inflammatory disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1117687

Funding Status
Closed

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Funded Activity Summary

Despite knowing a lot about immunity in a mice, functional analysis of the human immune system has been a major challenge. I will study defects of immune cells in humans with gene mutations that cause an antibody deficiency. With new insights from these unique clinical samples, I will functionally dissect human immune responses, directly translate these to chronic inflammatory disease, and provide implications for future vaccine development and cancer treatment.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Research Fellowships

Funding Amount: $631,370.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural Immunology and Immunochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

B cells | antibody | autoimmune disease | immunodeficiency | molecular immunology

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