The effect of α-actinin 3 deficiency on regulation of skeletal muscle mass in health and disease.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1114935

Funding Status
Closed

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Funded Activity Summary

A common genetic variant results in absence of the fast muscle fibre protein ?-actinin-3 in more than one billion humans worldwide. Loss of ?-actinin-3 influences elite athletic performance, muscle bulk and strength in the general population, and disease severity in muscle wasting conditions. The goal of this study is to understand how ?-actinin-3 regulates muscle mass so that individuals at increased risk of muscle wasting may be identified and treated accordingly.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Postgraduate Scholarships

Funding Amount: $84,800.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genetics not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

genetic risk factors | genotype | muscle disease | muscle wasting | signalling pathways

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