Platelet Derived Growth Factor Mediated Activation and Rejuvenation of Endogenous Cardiac Stem Cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1114472

Funding Status
Closed

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Funded Activity Summary

The burden of heart failure is underpinned by the heart’s limited capacity for self-repair after injury. Recent evidence shows that PDGF can improve heart function by activating and rejuvenating resident heart stem cells. This project will build on over a decade of preliminary work in mice, validating our results in a preclinical large animal model. Outcomes of this project include expedited progression of this promising therapy where thousands of heart failure patients could one-day benefit.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Postgraduate Scholarships

Funding Amount: $102,345.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

animal model | heart failure | myocardial infarction | regenerative medicine | translational research

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