Characterising the molecular basis of cystic kidney diseases using kidney organoids created by directed differentiation of patient-derived, induced pluripotent stem cells.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1114409

Funding Status
Closed

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Funded Activity Summary

Inherited genetic mutations cause almost half of chronic kidney diseases in children. In most cases we do not know what the mutation is or how it causes kidney disease. In this study we will turn skin cells from children with kidney disease into stem cells and then use these to make a mini-kidney in a dish. This will act as a model of kidney disease allowing us to understand what the problem is at the level of changes within the cells. This may result in new ways of treating kidney disease.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Postgraduate Scholarships

Funding Amount: $122,714.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genomics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

genetic analysis | paediatric | regenerative medicine | renal cystic disease | stem cells

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