Role of sphingolipid signalling in hepatic insulin resistance and its application in prediction of risk for type 2 diabetes and prediabetes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1113527

Funding Status
Closed

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Funded Activity Summary

Type 2 diabetes is expected to reach epidemic proportions in the coming decades. Prediabetes is usually unrecognized and constitutes a major public health concern that needs earlier interventions, because the majority of prediabetic subjects proceed to T2D. We have identified an enzyme that plays an important role in insulin signalling. The possibility is that the level or activity of this enzyme is a potential biomarker of the prediabetes state and could be also used as a target

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2020

Funding Scheme: Targeted Calls

Funding Amount: $563,305.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

diabetes mellitus | insulin resistance | insulin signalling | liver metabolism | signalling pathways

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