Ceramides and Metabolic Disease

Funding Activity

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Funded Activity Summary

In patients predisposed to metabolic diseases, excessive fats get delivered to various tissues. About 10 to 15% are converted into sphingolipids, many of which have deleterious effects on tissue function. Blocking sphingolipid production prevents diabetes and most cardiovascular diseases in rodents. We seek to better understand these mechanisms and determine how the observations can be translated into new therapies and better clinical outcomes.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2020

Funding Scheme: Research Fellowships

Funding Amount: $697,606.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

glucose homeostasis | insulin action | insulin resistance syndrome | lipid metabolism | metabolic disorders