The role of the neuronal epigenome in natural brain ageing and the progression of Alzheimer’s disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1111206

Funding Status
Closed

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Funded Activity Summary

Most cases of Alzheimer's disease are sporadic or late onset, with only ~5% of cases being familial, suggesting a potential role for epigenetics. This project aims to profile the human brain epigenome throughout normal ageing and in Alzheimer's disease so we can determine how disturbed epigenetic states may affect brain function. This research will provide new insights into the role of the epigenome in Alzheimer's disease, enabling crucial advances in understanding its origins.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Targeted Calls

Funding Amount: $584,644.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

epigenetics | genomics | methylation | neurodegenerative disorders | neurogenetics

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