Targeting the canonical Wnt signalling pathway to promote central nervous system remyelination in vivo

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1111041

Funding Status
Closed

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Funded Activity Summary

Multiple Sclerosis (MS) occurs when immune cells attack the sheaths, called myelin, that cover and protect nerve connections. If myelin is damaged nerve cells cannot function properly, leading to severe disability. The brain has a group of cells that could potentially replace damaged myelin, but as MS worsens these cells are blocked in a state where they cannot help in repair. I will remove a signal specifically from these cells and determine if this unblocks them resulting myelin repair.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Early Career Fellowships

Funding Amount: $314,644.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

multiple sclerosis (MS) | myelination | oligodendrocytes | remyelination | repair

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