Investigating the synergistic role of brain-derived neurotrophic factor (BDNF) and estradiol on parvalbumin-mediated cognitive function: relevance to dementia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1109959

Funding Status
Closed

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Funded Activity Summary

Estrogen-based therapy may improve cognitive functioning in dementia patients. However, more detailed knowledge is required to ensure safe and effective targeted treatment is provided. I propose to examine, in mouse models, the mechanistic functioning of estrogen signalling in key brain regions involved in cognition. Unravelling the way estrogen impart its beneficial effect can lead to the development of effective treatments for dementia and many other devastating neurological diseases.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Targeted Calls

Funding Amount: $589,644.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurosciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cognition | dementia | gender differences | neurobiology | neuroendocrinology

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