De novo mutations and the pathogenesis of childhood-onset autoimmune disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1108800

Funding Status
Closed

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Funded Activity Summary

This project aims to reveal the gene abnormalities that cause devastating autoimmune diseases to develop in some children, such as Type 1 diabetes, juvenile arthritis and autoimmune destruction of blood cells. The project will use new technologies to identify alterations in the DNA sequence of a child compared to either of their parents, and to test suspicious DNA alterations in laboratory mice in order to understand the gene effects and evaluate new treatments.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $1,406,510.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

de novo mutations | haemolytic anaemia | immunological tolerance | thrombocytopenia | type 1 diabetes mellitus (insulin-dependent diabetes mellitus)

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