Glycan-glycan interactions between bacterial pathogens and host cells: A novel mechanism of bacterial adherence, a new opportunity for strategies to treat and prevent disease and a new paradigm in interactions between macromolecules.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1108124

Funding Status
Closed

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Funded Activity Summary

Cell surface carbohydrates are ubiquitous throughout nature. Human cell surface carbohydrates are specifically targeted by microbial proteins. These interactions are crucial in causing disease. We have recently shown that the carbohydrates on our cells and those on pathogenic bacteria can interact with one another. Understanding the nature and role of these newly discovered interactions may lead to strategies to block them via new drugs and vaccines.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $1,059,344.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adherence | bacterial pathogenesis | glycobiology | glycosaminoglycans | lipopolysaccharide

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