NLRC5, a new regulator of Helicobacter-induced inflammation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1107930

Funding Status
Closed

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Funded Activity Summary

Helicobacter pylori lives in the stomach of half the world’s population and is a major cause of human disease, including cancer. The body fights H. pylori infection by mobilising white blood cells to the stomach lining, resulting in inflammation. We have evidence that H. pylori can attenuate this inflammation by targeting a host protein, NLRC5. This project will determine the role of NLRC5 in preventing inflammation and cancer due to H. pylori infection.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $640,136.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Microbiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Helicobacter pylori | chronic infection | host/pathogen interaction | pathogenesis | pathogenic mechanisms

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