Role of the EHF transcription factor in regulating the differentiation status of colon cancers

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1107831

Funding Status
Closed

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Funded Activity Summary

New treatment strategies for colon cancer are urgently needed. This application will test a novel approach for treating colon cancer based on the re-induction of differentiation of colon cancer cells, by reactivating a gene called EHF. We expect this to reduce the propensity for colon cancer cells to spread to distant organs and to increase their sensitivity to chemotherpay. This has the potential to significantly benefit the clinical management of patients with this disease.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $621,950.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

colon cancer | colon cancer metastasis | colonic epithelium | differentiation | transcriptional regulation

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