The role of mutant cyclin F in amyotrophic lateral sclerosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1107644

Funding Status
Closed

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Funded Activity Summary

Amyotrophic lateral sclerosis (ALS, also known as motor neuron disease, MND) is characterised by rapid paralysis leading to death within 2 to 5 years of onset. There are no effective diagnostic tests or treatments. Confusion remains around the primary cause of paralysis. We recently discovered ALS gene mutations that disrupt normal nerve function, a process known as abnormal protostasis. This gives us a unique opportunity to unlock the primary cause of paralysis and develop animal models of ALS

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $1,012,933.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

amyotrophic lateral sclerosis | motor neuron disease (MND) | mouse models | neurodegeneration | pathogenic mechanisms

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