Neuroprotective functions of autophagy regulators in Alzheimer's disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1107109

Funding Status
Closed

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Funded Activity Summary

The accumulation of the beta amyloid protein has a central role in AD and enhancing its removal improves memory loss in animal AD models. This project builds on my recent finding of regulators of a cell housekeeping system, “autophagy” which accelerate removal of beta amyloid in cells. This study will advance knowledge into the protective functions of the autophagy regulators in reducing AD symptoms. Findings from this work might provide the basis for developing effective anti-AD therapeutics.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2020

Funding Scheme: Targeted Calls

Funding Amount: $434,644.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

AMP-activated protein kinase | amyloid beta-protein | autophagy | neurodegeneration | protein phosphatase

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