Defining the Interaction of HIV with the Interferon System in Initial Mucosal Infection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1106442

Funding Status
Closed

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Funded Activity Summary

Very early after virus exposure, immune cells secrete interferons that help limit the spread of viruses within the body. We will investigate the complex interplay between HIV and the interferon system, especially how HIV inhibits the early induction of interferon to aid its spread and then how the body later restores the interferon response. We will also examine how HIV manipulates the interferon system in order to persistent latent reservoirs within tissues.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $867,716.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

dendritic cell | human immunodeficiency virus (HIV) | interferon (IFN) | macrophages | sexual health

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