SETD7-dependent regulation of Hippo/YAP and Wnt/beta-catenin pathways in the intestine

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1104433

Funding Status
Closed

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Funded Activity Summary

Colon cancer accounts for approximately 10% of all cancer-related deaths in Australia. One of the most common causes of colon cancer is a mutation in a signalling pathway called the Wnt/beta-catenin pathway. Despite this knowledge, there are currently no drugs that directly target this pathway to treat colon cancer. We have now identified a new way to control this pathway and have developed a potent and specific drug to block activation of this pathway.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $601,950.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Wnt signalling | cancer | intestine | methylation | regeneration

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