GPR88 as a novel target for fronto-striatal dysfunction in schizophrenia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1104371

Funding Status
Closed

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Funded Activity Summary

GPR88 is a protein that is specifically found in the striatum, one of the main brain regions involved in schizophrenia. Studies in mice have showed that GPR88 may have a role in learning and memory; our early studies show that GPR88 controls the activity of a population of cells in the striatum. This project will determine the mechanism by which GPR88 controls the function of the striatum and how this translates into regulating brain circuitry and learning and memory relevant to schizophrenia.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $606,966.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G protein-coupled receptors | cognition | schizophrenia and related disorders | signal transduction | striatum

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