How do anaesthetics work? A rational basis for safer general anaesthesia.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1104259

Funding Status
Closed

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Funded Activity Summary

General anaesthetics are a mainstay of modern medicine, but have a small safety margin, requiring skilled anaesthetists for their safe use. There is growing evidence that general anaesthetic exposure may have long-term effects on brain function in both newborns and the elderly. This project will provide a detailed molecular description of anaesthetic action and specificity. It will provide the basis for designing new anaesthetics that are safer, both immediately and for long-term brain function.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $592,008.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biomolecular Modelling and Design

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anaesthetics | cognitive impairment | ligand-gated ion channels | modelling | molecular mechanisms

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