Defining the function of ROCK in establishing a tumour-promoting microenvironment

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1103712

Funding Status
Closed

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Funded Activity Summary

Cancer’s spread from its primary to secondary sites causes most cancer-related deaths. As cancers grow and spread, their internal structure is modified. Immune cells within the cancer begin to behave differently to the same types of cells in normal tissues, promoting its spread. We have discovered that many of these changes are regulated by a protein called ROCK. We plan to study how ROCK controls such a wide range of tumour promoting processes.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $611,950.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer biology | microenvironment | signalling pathways | transgenic mouse | tumour progression

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