Brain metal neurochemistry: mechanism-driven drug discovery for neurodegeneration

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1103703

Funding Status
Closed

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Funded Activity Summary

Alzheimer’s disease (AD) is a complex disease where certain proteins congeal in the brain and metals accumulate. This project investigates the function of the proteins in microscopically transporting the metals. It will also look for tests that predict the onset of AD by measuring iron and iron related proteins by using special brain imaging (MRI), and measurements in spinal fluid. Finally, it will test drug candidates that target the metals, in animal models of AD, and in early clinical trials.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2020

Funding Scheme: Research Fellowships

Funding Amount: $851,980.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | biomarkers | iron | metal metabolism | protein biochemistry

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