How do cross-reactive memory B cells affect influenza vaccine titers?

Funding Activity

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Funded Activity Summary

Influenza vaccines are updated frequently to protect against the highly variable influenza virus. Despite careful selection of vaccine viruses, most influenza vaccines provide only modest protection and protection is poor some years. In turn, the response to vaccination varies between individuals. This probably reflects complex and variable histories of influenza infection and vaccination. The project investigates how past influenza exposure influences vaccine responses and effectiveness.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $798,049.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural Immunology and Immunochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

B cells | antibody | antigenic variation | influenza virus | vaccination immunology