A signalling endosomal network in T cell activation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1102730

Funding Status
Closed

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Funded Activity Summary

T lymphocytes play a central role in the adaptive immune response, which specifically targets pathogens and cancer cells and creates the immunological memory. Activation of sometimes as little as one single receptor on a T cell triggers a cellular signal that rapidly expands and branches out in a multitude of sub-signals. Here we will use a combination of novel microscopy approaches to visualise how a network of dedicated intracellular compartments is in charge of these processes.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $428,016.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Protein Trafficking

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell activation | endosomes | imaging | membrane signalling | membrane trafficking

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