Systems biology to identify molecular targets for vascular disease treatment (SysVasc), with a focus on atherosclerotic plaque instability

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1102158

Funding Status
Closed

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Funded Activity Summary

Heart attacks are caused by rupture of atherosclerotic deposits (plaques) in vessel walls, which results in clot formation ultimately causing vessel occlusion. In collaboration with strong European collaborators, we will use modern high-throughput technologies in a large patient cohort as well as in a newly generated mouse model to discover the causative proteins, genes and their regulators. This will allow identifying individuals at risk and developing novel therapies to prevent heart attacks.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Targeted Calls

Funding Amount: $450,721.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

atherosclerosis | cardiovascular | plaque rupture | proteomics | systems biology

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