Neuregulin 1 Type III Overexpression and Schizophrenia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1102012

Funding Status
Closed

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Funded Activity Summary

Neuregulin (NRG1) is a neuronal growth factor and regulates the development of cortical inhibitory interneurons. Human studies suggest that NRG1 type III overexpression and deficient interneuron development underlie schizophrenia. Thus, we have developed a mouse overexpressing Nrg1 type III to discover mechanisms behind NRG1-related cortical pathology and schizophrenia-like behaviours and to clarify whether NRG1 type III interacts with environmental risk factors for the disorder.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $651,966.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

animal model | behaviour | cannabis | gamma-aminobutyric acid (GABA) | schizophrenia

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