The role of Porphyromonas gingivalis outer membrane vesicle biogenesis in virulence and immunomodulation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1101935

Funding Status
Closed

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Funded Activity Summary

Porphyromonas gingivalis is a keystone pathogen in chronic periodontitis. This bacterium exists as part of a biofilm on the surface of the tooth and selectively packages enzymes, toxins and antigens on to vesicles that penetrate host tissue and cause the inflammatory response that is associated with disease progression. In this study we will determine the host response to vesicles and determine the role of a specific protein in vesicle biogenesis.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $734,288.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Dentistry not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Porphyromonas gingivalis | bacterial biofilm | bacterial pathogenesis | innate immunity | periodontitis

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