Protecting synaptic connectivity in Alzheimer's disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1100324

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

In Alzheimer’s disease, connections between neurons (synapses) are progressively damaged. The BACE inhibitor class of drugs entering Phase III clinical trials may slow the pace of neurodegeneration in patients with dementia. However, these drugs may simultaneously have negative effects on synapse function, learning and memory. This study will assess the effect of BACE inhibition on synapse properties and cognition and identify the contribution of key proteins affected by this treatment.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2022

Funding Scheme: Targeted Calls

Funding Amount: $573,573.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | memory | neuroscience | synapse formation | synaptic plasticity

Related Links