The precise steps in dendritic cell development

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1100033

Funding Status
Closed

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Funded Activity Summary

Dendritic cells (DCs) are the body’s sentinels, with three specialized subtypes. They monitor for infections and cancer and then activate immune T cells to clear it. Interestingly, they can all arise from a single cell, but the precise steps are unknown. By literally filming this process and analyzing the movie, we hope to draw the ‘family trees’ that lead to their generation. This knowledge will offer crucial clues as to how to boost or reduce their numbers for medical applications.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $330,998.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

clonal diversity | dendritic cell lineages | differentiation | image analysis | mathematical modelling

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