A systems-biology approach to understanding the beneficial heterologous effects of neonatal BCG vaccination in a Melbourne-based randomised controlled trial

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1099680

Funding Status
Closed

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Funded Activity Summary

BCG vaccine (usually used to protect against TB) also enhances the immune system of young babies to protect them against infections other than TB. We have a large collection of blood samples from a study in which babies were randomised to be given BCG vaccine at birth or no BCG. We will use these to understand the immunological and molecular mechanisms by which BCG boosts the immune system to protect against infections other than TB.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $846,853.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

innate immunity | neonate | systems biology | transcription | vaccination immunology

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