Novel Anti-Infective Agents that Act by Enhancing the Host Innate Response

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1099428

Funding Status
Closed

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Funded Activity Summary

Antibiotic resistance is one of our major challenges, with fears expressed that we may soon run out of effective antibiotics for the treatment of infections. The goal of this project is to develop a novel class of antibiotics that acts by enhancing our immune response to infection rather than attacking the bacteria themselves, and therefore will not be susceptible to the development of bacterial resistance. These agents inhibit the degradation of a key enzyme involved in combating infections.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $655,482.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

drug conjugation | inducible nitric oxide synthase (iNOS) | macrophages | peptide inhibitors | suppressor of cytokine signalling (SOCS)

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