Novel epigenetic regulatory mechanisms in Moraxella catarrhalis and non-typeable Haemophilus influenzae: impact on vaccine development and role in pathobiology

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1099279

Funding Status
Closed

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Funded Activity Summary

Moraxella catarrhalis (Mcat) and non-typeable Haemophilus influenzae (NTHI) are two major causes of middle ear infections in children, and respiratory disease in adults. This project aims to characterise novel regulatory mechanisms associated with disease isolates of these bacteria. This research will aid vaccine development by defining the repertoire of stably expressed potential vaccine targets of Mcat and NTHi, and will improve our understanding of host-pathogen interactions.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $626,979.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Haemophilus influenzae | Moraxella catarrhalis | chronic obstructive pulmonary disease (COPD) | epigenetics | otitis media

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