Functional characterization and therapeutic targeting of the novel long noncoding RNA MYCN-AS

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1099025

Funding Status
Closed

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Funded Activity Summary

Cancer is the most common cause of death from diseases in children. Neuroblastoma is the most common solid tumour in early childhood. In this application, we will establish the role of gene amplification of a novel long non-protein-coding RNA in blocking tumour suppressor gene expression and promoting neuroblastoma progression. We will also establish the anti-cancer efficacy of a novel therapy targeting the long non-protein-coding RNA.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $646,979.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Therapy (excl. Chemotherapy and Radiation Therapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA binding proteins | cancer therapy | neuroblastoma | transcriptional regulation | tumour suppressor gene

Related Links

ACN 633 798 857