Blocking the factor XII- kallikrein pathway to limit abdominal aortic aneurysm

Funding Activity

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Funded Activity Summary

Artery weakening is present in 2-5% of older adults and is an important cause of sudden death. The investigators have generated substantial preliminary data from a previous NHMRC project implicating the contact pathway in the process of artery weakening. In the current project the investigators will examine the ability of agents which are currently available or being developed for patient use in limiting the process of artery degeneration using established pre-clinical models.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $686,995.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

abdominal aortic aneurysm | biology | mouse models | peripheral vascular disease | treatment planning