Using mechanotransduction to regulate stem cell fate in heart tissue

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1098449

Funding Status
Closed

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Funded Activity Summary

Emerging new interdisciplinary field, mechanotransduction, combines efforts from biology, engineering, and material science to understand how cells sense/feel their surroundings mechanically e.g. soft vs. stiff and transfer these signals to biochemical signalling to initiate cellular changes. This project aims to develop high-throughput hydrogel platform with stiffness patterns to study cellular mechanosensing mechanism and to generate better heart muscle cells for heart stem cell therapy.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $385,983.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

biomaterials | extracellular matrix | mechanotransduction | regenerative medicine | stem cells

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