Cell Survival Pathways as Potential Targets in Breast Cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1094320

Funding Status
Closed

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Funded Activity Summary

Cancer cells are characterised by their capacity for relentless growth, survival and evasion of cell death. This proposal will use patient derived xenograft models of primary breast cancer to test the hypothesis that addition of BH3-mimetics could improve response to anti-HER2 therapy. This technique involves transplantation of patient tumours into immune-compromised mice. This represents a useful method for testing new agents.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Postgraduate Scholarships

Funding Amount: $142,914.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

apoptosis | breast cancer | mammary gland cancer | mouse models | xenografts

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