HtrA4-induced endothelial dysfunction in early-onset preeclampsia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1093519

Funding Status
Closed

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Funded Activity Summary

Preeclampsia (PE), a life-threatening disorder of pregnancy, is characterized by a sudden increase in blood pressure in association with wide-spread endothelial dysfunction. Placenta-derived factors are believed to cause PE development. Our recent studies have identified that HtrA4, a placenta-specific serine protease may contribute to endothelial dysfunction. This study will investigate the mechanisms of HtrA4-induced endothelial dysfunction.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Postgraduate Scholarships

Funding Amount: $86,073.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Reproduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

placentation | pregnancy complications | protein biochemistry | protein expression | reproduction

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