Humanisation and pre-clinical validation of a therapeutic anti-cancer antibody

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1093304

Funding Status
Closed

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Funded Activity Summary

This grant will develop a novel antibody against a protease expressed on cancer cells. Preclinical studies, and antibody humanisation, will be performed. This project will also provide vital information on optimal therapeutic approaches with the antibody that can be ultimately taken into human trials.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Development Grants

Funding Amount: $699,136.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Therapy (excl. Chemotherapy and Radiation Therapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

ErbB receptors | Notch signalling pathway | antibody cancer therapy | antibody engineering | metalloproteinase

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