Broad Spectrum Inhibition of an Enzyme Antibiotic Target

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1091976

Funding Status
Closed

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Funded Activity Summary

There is a well-documented need to replenish the antibiotic pipeline with new products to combat the rise of drug resistant bacteria. In this project, the enzyme dihydrodipicolinate synthase (DHDPS) is targetted which is essential to bacterial viability. A number of independent but synergistic drug discovery approaches are investigated to develop and test DHDPS inhibitors in the pursuit of a novel class of antibiotics.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2019

Funding Scheme: Early Career Fellowships

Funding Amount: $321,534.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibiotics | drug design | enzyme inhibitors | enzyme kinetics | protein biochemistry

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