Improving endothelial dysfunction in diabetes-associated vascular diseases with Nrf2 activators

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1091003

Funding Status
Closed

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Funded Activity Summary

Diabetic patients have a greater risk of developing cardiovascular diseases as compared to the general population. This is largely attributed to the impact the diabetic environment has on the endothelium (inner layer of the blood vessel). Indeed, clinical studies have shown that impaired endothelial function occurs prior to the development of cardiovascular diseases. Hence, we propose to study a novel way to improve endothelial function by limiting oxidative stress and inflammatory pathways.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2020

Funding Scheme: Early Career Fellowships

Funding Amount: $340,039.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

atherosclerosis | diabetes | nitric oxide | peptides | vascular biology

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