Molecular profiling of the immunoglobulin proteome in primary Sjögren’s syndrome

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1090759

Funding Status
Closed

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Funded Activity Summary

Primary Sjögren’s syndrome is a common autoimmune disease. The patients have high levels of circulating immunoglobulins (Igs) in their blood-a hallmark of the disorder. The applicant proposes to sequence these Igs and identify their so-called variable region molecular signatures. These signatures can then be used in a mass spectrometric-based diagnostic platform to identify unique clones in patients as early markers of the disease process, and hopefully lead to more relevant diagnostic markers.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2019

Funding Scheme: Early Career Fellowships

Funding Amount: $322,460.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Sjogren's syndrome | autoantibodies | autoimmune disease | biomarkers | proteome analysis

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