Understanding the critical mechanisms that govern regulatory T cell life and death decisions

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1089072

Funding Status
Closed

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Funded Activity Summary

Autoimmune diseases impose an increasingly large health burden. Treg cells prevents the immune system from attacking “self” offering the promise of using these cells to restore immune balance in autoimmune diseases. However, there are currently no protocols that reliably modify Treg cell numbers. This study will elucidate the mechanisms that govern Treg cell survival and death, revealing potential molecular targets to manipulate the quality and quantity of Treg cell for therapeutic benefit.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2019

Funding Scheme: Early Career Fellowships

Funding Amount: $338,811.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

apoptosis | autoimmunity | immune tolerance | mouse genetics | regulatory T cells

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