Improved risk assessment for drugs causing cardiac arrhythmias

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1088214

Funding Status
Closed

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Funded Activity Summary

Fatal heart rhythm disturbances are an all too common side effect of many drugs. Tests that are in place to guard against this are effective, but widely considered too stringent, meaning the development of potentially useful new therapeutics has been hampered. This study will characterise the precise mechanisms by which drugs cause arrhythmias and identify specific patterns on patient ECGs associated with the risk of rhythm disturbances that can be used in more effective clinical testing.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $638,166.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical Pharmacology and Therapeutics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

arrhythmia | computer simulation | drug screening | electrocardiogram (ECG) | pharmacology

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