Disruption to intracellular trafficking as a central pathogenic mechanism in amyotrophic lateral sclerosis (ALS)

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1086887

Funding Status
Closed

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Funded Activity Summary

There are several different forms of ALS (MND), but the disease appears very similar in terms of symptoms and pathology. We have identified a common disease process shared by several different forms of ALS, which suggests that this is the underlying mechanism by which motor neurons die. This study will investigate whether we can develop new drug targets based on this mechanism in animal disease models. This may ultimately assist in the development of new treatments for ALS.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $688,157.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

ageing | apoptosis of neurons | microtubules | motor neuron disease (MND) | trafficking

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