Gene-environment interactions modulating cognition and dementia in Huntington’s disease

Funding Activity

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Funded Activity Summary

We are investigating mechanisms whereby cognitive symptoms, culminating in dementia, occur in a fatal brain disease, Huntington’s. We will explore how the ‘genetic stutter’ affects the brain at the level of molecules and cells, which will help identify targets for future treatment. We will also establish how environmental factors, including cognitive stimulation, physical activity and stress, modulate dementia. This will inform the development of treatments for this currently incurable disease.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $394,425.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Huntington's disease | dementia | dementia-related decline in memory | environmental influences | neurodegenerative disorders