microRNAs and liver cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1084964

Funding Status
Closed

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Funded Activity Summary

Hepatocellular carcinoma (HCC), or liver cancer, is a major global problem. Most people present with advanced disease and current therapies are relatively ineffective. Small RNAs, called microRNAs are a new form of therapy that may present new options for patients with HCC. We have characterised a microRNA that is a powerful inhibitor of HCC growth both in cells and in preclinical animal models. This project will characterise the microRNA’s function in HCC and as a potential therapeutic.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $700,751.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Therapy (excl. Chemotherapy and Radiation Therapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

epidermal growth factor receptor (EGFR) | hepatocellular carcinoma | kinase inhibitors | microrna | translational research

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