PIPS regulate the type 1 angiotensin receptor

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1084462

Funding Status
Closed

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Funded Activity Summary

The hormone angiotensin II (AngII) contributes broadly to the cardiovascular, endocrine, neural and metabolic systems. It binds to the angiotensin II type 1 (AT1) receptor and inappropriate activity leads to hypertension. Using a range of molecular and biophysical approaches and the angiotensin receptor as a model GPCR, we will study the role of the cell membrane in AT1 activation which may lead to new approaches for drug design.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $608,123.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

G protein-coupled receptors | angiotensin receptor | biophysics | membranes | molecular pharmacology

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