Zinc as an antimicrobial agent and its effect on the pathogenesis of Group A Streptococcus

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1084460

Funding Status
Closed

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Funded Activity Summary

This proposal focuses on Group A Streptococcus (GAS), a human pathogen estimated to cause 600,000 human deaths per year. We have shown that the host immune system uses zinc as an antibacterial agent and that GAS has processes that protect against zinc overload. We will determine the way in which zinc mobilization controls GAS infection and how GAS responds to to an increase in zinc concentration. The results will provide new insights into zinc’s role in protection against bacterial infections.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $352,359.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Streptococcus pyogenes | bacterial pathogenesis | infectious diseases | neutrophils | zinc

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