Liver lipotoxicity and NASH: mechanistic roles of free cholesterol, saturated FFA, JNK1 and TLR4

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1084136

Funding Status
Closed

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Funded Activity Summary

Non-alcoholic fatty liver disease (NAFLD) occurs in overweight people, diabetes and with high blood pressure and raised cholesterol. This research is about how cholesterol in liver cells interacts with long chain fatty acids to cause injury and inflammation (steatohepatitis, NASH) in NAFLD.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $429,712.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Toll-like receptors | c-Jun/JNK kinase | cholesterol | fatty acids | fatty liver disease

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