A preclinical humanized chimeric model to investigate novel therapeutic strategies against breast cancer bone metastasis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1082313

Funding Status
Closed

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Funded Activity Summary

Using the humanized in-vivo model presented, researchers are in a unique position to develop and evaluate novel therapeutic strategies against breast cancer bone metastasis at multiple intervention points from the primary tumour to bone metastasis. This model makes it possible to study anti-cancer and anti-resorptive effects of human-specific drugs such as the monoclonal antibody Denosumab. The model eventually may help to decrease morbidity and mortality of breast cancer patients.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $696,362.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Solid Tumours

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bone metastasis | breast cancer metastases | haematology | stem cells | tissue engineering

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